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Tosyl chloride CAS 98-59-9

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Tosyl chloride CAS 98-59-9
Tosyl chloride (TsCl), azaman samfurin sinadarai mai kyau, ana amfani dashi sosai a cikin rini, magunguna, da masana'antar kashe qwari. A cikin masana'antar rini, an fi amfani da shi don kera masu tsaka-tsaki don tarwatsawa, rini na kankara, da rini na acid; a cikin masana'antar harhada magunguna, ana amfani da Littafin sinadarai galibi don samar da sulfonamides, mesulfonate, da sauransu; a cikin masana'antar magungunan kashe qwari, an fi amfani da shi a cikin samar da mesotrione, sulfotrione, lafiya metalaxyl, da sauransu.
Akwai manyan hanyoyin gargajiya guda biyu don TsCl: 1. Ana samar da shi ta hanyar chlorination acid na toluene da wuce haddi na chlorosulfonic a ƙananan zafin jiki. Wannan hanya tana samar da o-toluenesulfonyl chloride tare da babban abun ciki, kuma p-toluenesulfonyl chloride shine samfurin ta, kuma duka biyu Yana da wuya a rabu kuma yana cinye makamashi mai yawa; 2. Toluene da chlorosulfonic acid kai tsaye chlorinated tare da wuce haddi chlorosulfonic acid a gaban wasu gishiri da kuma a wani zazzabi. Ko da yake wannan hanya yana da mafi girma samfurin rabo na toluenesulfonyl chloride, da tsarkakewa rabo Hanyar da sauki da kuma cinye low makamashi. Duk da haka, saboda in mun gwada da high dauki zafin jiki, da rabu sulfonated man ya ƙunshi high sulfones kuma yana da low amfani darajar. Ainihin jimlar yawan amfanin ƙasa kusan kashi 70 ne kawai a cikin Littafin sinadarai. Bugu da ƙari, duka hanyoyin biyu suna da yawan amfani da albarkatun ƙasa na chlorosulfonic acid kuma sharar sulfuric acid da aka samar ya yi yawa, wanda ba shi da amfani ga amfani da masana'antu da magani. Akwai kuma rahotanni don inganta hanyar. Na farko, da p-toluenesulfonyl chloride a cikin dauki cakuda ne cikakken crystallized a karkashin wasu yanayi da kuma crystal barbashi suna kara girma. Ana amfani da hanyar tacewa kai tsaye ba tare da hydrolysis ba don cire p-toluenesulfonyl chloride daga cakuda. Duk da haka, a halin yanzu akwai wasu matsaloli wajen zaɓar kayan aikin masana'antu kuma zuba jari yana da yawa. Ingantaccen tsari: An zaɓi masu haɓakawa masu dacewa da sauran mafi kyawun yanayin tsari.
Tosyl chloride (TsCl) wani farin kristal ne mai walƙiya tare da wurin narkewa na 69-71°C. Yana da mahimmancin ƙwayar ƙwayar ƙwayar cuta ta tsakiya kuma ana amfani da shi a cikin kira na chloramphenicol, chloramphenicol-T, thiamphenicol da sauran kwayoyi. .


  • Suna:Tosyl chloride CAS 98-59-9
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    Tags samfurin

    Gabatarwar samfur

    osyl chloride (TsCl), a matsayin samfurin sinadarai mai kyau, ana amfani da shi sosai a cikin rini, magunguna, da masana'antar magungunan kashe qwari. A cikin masana'antar rini, an fi amfani da shi don kera masu tsaka-tsaki don tarwatsawa, rini na kankara, da rini na acid; a cikin masana'antar harhada magunguna, ana amfani da Littafin sinadarai galibi don samar da sulfonamides, mesulfonate, da sauransu; a cikin masana'antar magungunan kashe qwari, an fi amfani da shi a cikin samar da mesotrione, sulfotrione, lafiya metalaxyl, da sauransu.

    Tosyl chloride (TsCl) wani farin kristal ne mai walƙiya tare da wurin narkewa na 69-71°C.

    Filin aikace-aikace

    Yana da mahimmancin ƙwayar ƙwayar ƙwayar cuta ta tsakiya kuma ana amfani da shi a cikin kira na chloramphenicol, chloramphenicol-T, thiamphenicol da sauran kwayoyi. .

    Bayanin gini

    Tosyl chloride

    CAS 98-59-9

    Tsarin kwayoyin halitta C7H7ClO2S

    Nauyin kwayoyin halitta 190.65

    Lambar EINECS 202-684-8

    Matsayin narkewa 65-69 ° C (lit.)

    Matsayin tafasa 134 °C 10 mm Hg (lit.)

    Yawaita 1,006 g/cm3

    Matsakaicin zafin jiki na 128 ° C

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